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   OSTO Presents
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   Endocrine Manifestations of Systemic Autoimmune Diseases, Volume 9

   Type      : eBook
   ISBN      : 0444531726
   Publisher : Elsevier Science
   Format    : PDF
   Pub date  : June 18, 2008
   Size      : 02 Disks x 2.88MB
   Rls date  : 07/22/2008

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   This book is one of the first to evaluate the role of Steroids in 
   autoimmune rheumatic diseases from the basic mechanisms to the clinical 
   involvements and focuses on the importance of steroidal hormones in the 
   pathogenesis and therapeutical management of the autoimmune rheumatic 
   diseases. In particular, the chapters analyze the mechanisms of action 
   and the involvement of adrenal steroids (glucocorticoids) in the 
   neuroendocrine immune system, including the effects on elderly. The 
   perturbations of the HPA axis as source of altered steroidal sythesis 
   will be discussed and related to some interesting pathological 
   conditions often complicating the autoimmune rheumatic diseases susch as 
   psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex 
   hormones), several chapters will discuss clinical and epidemiological 
   evidences of their role, as well as their effects as risk factors in 
   autoimmune rheumatic diseases, including a section in Pediatrics. 
   
   *The premier issue evaluating the role of Steroids in autoimmune 
   rheumatic diseases from the basic mechanisms to the clinical 
   involvements 
   *Documents the latest research and indicate recent and coming new 
   therapeutical-biological approaches to the therapy 
   *The book will present therapeutical perspectives concerning the new 
   glucocorticoids, and the effects of biological drugs on their synthesis 

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   http://www.amazon.com/exec/obidos/tg/detail/-/0444531726/

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